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Japanese scientists announced the successful creation of nephrons - the structural element of the kidney from stem cells
According to RIA Novosti, a group of scientists from Okayama University in Japan announced the successful creation of nephrons - the structure-forming element of the kidney - from rat stem cells.
In the course of the experiment, scientists took somatic rat kidney stem cells, and then, by adding five types of proteins, through 3-4 weeks, they grew a cellular structure that coincides in structure with nephrons.
"The creation of organs from stem cells was a long-standing dream of mankind. It is already known about the successful creation of retinal cells, fragments of the brain and liver. But for the first time in the world, it was possible to achieve the reconstruction of a structure that strikingly coincides with the structure of a real kidney," the university said.
Nephrons are the structural unit of the kidney and are responsible for removing harmful substances from the blood, in the kidney there are about one million nephrons.
Scientists believe that the experiment will be the first step to research on the reconstruction of the kidney structure, which in the future can reveal new cardinal ways of treating chronic kidney disease.
Japan pays great attention to experiments on the creation of organs from stem cells. Studies in this field received additional impetus after in 2012 the Japanese professor Shinya Yamanaka was awarded the Nobel Prize for the creation in 2006 of a stem cell from a normal human skin cell. The cells are called induced pluripotent (multifunctional) stem cells-iPS. For eight years after the discovery of iPS cells, scientists have learned to grow from them cells of the heart muscle, intestine, pancreas, retina, blood, skin, nerve cells, female egg and sperm cells.
In September of this year, for the first time in the world, a team of scientists led by Masayo Takahashi from the RIKEN Institute carried out an operation for an eye retina transplantation, the cells of which were grown from artificial multifunctional stem cells iPS (induced pluripotent stem cells? IPS) created from 70- year-old female patient.